Anti-BK beta4 K+ channel [L18A/3R]

Absolute Antibody

Anti-BK beta4 K+ channel [L18A/3R]

9

This antibody is specific for BKBeta4. It shows no cross-reactivity against BKBeta1, BKBeta2 or BKBeta3. BKBeta4 is a regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. It modulates the calcium sensitivity and gating kinetics of

This antibody was used for immunoblotting on brain tissue from rats exposed to CVS and mouse hippocampi (Yu et al, 2018; PMID:30271963). Immunofluorescence was preformed on HEK293 cells and N2a neurons with this antibody (Chen et al, 2013; PMID:23504458). Transfected HEK293 cells were immunoblotted with this antibody (Chen et al, 2013; PMID:23504458). The hippocampi of rats were immunostained with this antibody. This assay was preformed in order to assess the integrity of mossy fiber pathway and whether MaxiK channel are expressed at mossy fiber axon and terminals (Cox et al, 2014; PMID:24486049). DRG (L4/L5) from rats was used for a western blot with this antibody (Zhang et al, 2012; PMID:22607137).

ImmunoFluorescence, Western Blot

Research Use Only

Monoclonal

L18A/3R

Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

1700058G18Rik; 2900045G12Rik; BK channel subunit beta-4; BKbeta4; calcium-activated potassium channel subunit beta-4; calcium-activated potassium channel, subfamily M subunit beta-4; charybdotoxin receptor subunit beta-4; k(VCA)beta-4; large conductance calcium-dependent potassium ion channel beta 4 subunit; maxi K channel subunit beta-4; slo-beta-4; Slowpoke beta 4

Mouse

IgG2a

Calcium-activated potassium channel subunit beta-4

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203