anti-Bmf, mAb (9G10)

AdipoGen Life Sciences

anti-Bmf, mAb (9G10)

10

Flow Cytometry, ImmunoPrecipitation, Western Blot

Research Use Only

Monoclonal

9G10

1 mg/ml

>95%

BMF

Bcl2 modifying factor

bcl-2-modifying factor

Rat

IgG2a

Bcl-2-modifying factor

Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis. - Monoclonal Antibody. Recognizes human and mouse Bmf. Detects several cross-reactivity bands of unknown identity in mice by western blot. Isotype: Rat IgG2akappa. Clone: 9G10. Applications: FACS, IP, WB. Liquid. In PBS containing 0.02% sodium azide. Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

-20°C,2°C to 8°C

12352203