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ProductsBack/anti-Bmf (mouse/rat), mAb (17A9)
Western blot using anti-Bmf (mouse/rat), mAb (17A9) (Prod. No. AG-20T-0131) detecting endogenous Bmf in mouse spleen, lymph node and thymus as two bands of ~25 and ~30 kDa, but not in tissues from two knock-out Bmf strains del 372 and del 376.
Western blot using anti-Bmf (mouse/rat), mAb (17A9) (Prod. No. AG-20T-0131) detecting endogenous Bmf in mouse spleen, lymph node and thymus as two bands of ~25 and ~30 kDa, but not in tissues from two knock-out Bmf strains del 372 and del 376.
Western blot using anti-Bmf (mouse/rat), mAb (17A9) (Prod. No. AG-20T-0131) detecting endogenous Bmf in mouse spleen, lymph node and thymus as two bands of ~25 and ~30 kDa, but not in tissues from two knock-out Bmf strains del 372 and del 376.

anti-Bmf (mouse/rat), mAb (17A9)

Research Use Only
AG-20T-0131
AdipoGen Life Sciences
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
DownloadMSDS
Product group Antibodies
ReactivityMouse, Rat
TargetBmf
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-Bmf (mouse/rat), mAb (17A9)
  • Delivery Days Customer
    10
  • Antibody Specificity
    Recognizes an epitope within the peptide sequence aa 13-27 of mouse and rat Bmf. Detects bands of ~25kDa and ~30kDa by Western blot, corresponding to endogenous Bmf and BmfL. Does not cross-react with human Bmf.
  • Applications
    Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    17A9
  • Concentration
    1 mg/ml
  • Estimated Purity
    >95%
  • Gene ID171543
  • Target name
    Bmf
  • Target description
    BCL2 modifying factor
  • Target synonyms
    AW260063; AW411872; bcl-2-modifying factor
  • Host
    Rat
  • Isotype
    IgG2a
  • Scientific Description
    Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis. - Monoclonal Antibody. Recognizes an epitope within the peptide sequence aa 13-27 of mouse and rat Bmf. Detects bands of ~25kDa and ~30kDa by Western blot, corresponding to endogenous Bmf and BmfL. Does not cross-react with human Bmf. Isotype: Rat IgG2akappa. Clone: 17A9. Applications: ELISA, FACS, ICC, IHC, IP, WB. Liquid. In PBS containing 0.02% sodium azide. Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203