Anti-Butyrylcholinesterase [11D8]

Absolute Antibody

Anti-Butyrylcholinesterase [11D8]

9

11D8 binds to both native and denatured human butyrylcholinesterase (HuBChE) with KD ~0.26 nM (determined by ELISA - 0.9 nM by SPR). Binding of 11D8 excludes binding of mAb B2 18-5, suggesting tht that bind to the same/similar epitope on huBChE. The antib

The percent active HuBChE bound to 11D8 in ELISAS is highest when the volume of plasma was lowest. 11D8 also binds to human albumin and so 11D8 is less suitable for immunopurification of huBChE from plasma compared to e.g. B2 18-5.

ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

11D8

BCHE

butyrylcholinesterase

acylcholine acylhydrolase; BCHED; butyrylcholine esterase; CHE1; CHE2; choline esterase II; cholinesterase; cholinesterase (serum) 2; cholinesterase 1; E1; pseudocholinesterase

Human

Cholinesterase

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203