Anti-C5a [Fab 102]
AB00989-23.0-BT
ApplicationsELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetC5
Overview
- SupplierAbsolute Antibody
- Product NameAnti-C5a [Fab 102]
- Delivery Days Customer9
- Antibody SpecificityFab 102 binds only to C5a and not to C5. This antibody is likely to recognise a conformational epitope because it failed to bind C5a when it was linked to microtiter plates. The epitope is outside the active site of C5a.
- Application Supplier NoteFab 102 has been used in ELISAs in order to specifically detect C5a and quantify C5a in human CSF (Stahel 1997). It can be used to block C5a binding to its receptor. mAbs to C5a may have a therapeutic benefit in sepsis/ARDS.
- ApplicationsELISA, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDFab 102
- Gene ID727
- Target nameC5
- Target descriptioncomplement C5
- Target synonymsanaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C5a; C5a anaphylatoxin; C5b; C5D; complement C5; complement component 5; CPAMD4; ECLZB; prepro-C5
- HostRabbit
- IsotypeIgG
- Protein IDP01031
- Protein NameComplement C5
- Scientific DescriptionThis chimeric rabbit antibody was made using the variable domain sequences of the original Mouse Fab format, for improved compatibility with existing reagents, assays and techniques.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203