Immunohistochemical staining of formalin fixed and paraffin embedded human colon tissue section using anti-CALD1 rabbit monoclonal antibody (Clone RM396) at a 1:100 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human colon tissue section using anti-CALD1 rabbit monoclonal antibody (Clone RM396) at a 1:100 dilution.
anti-CALD1 (human), Rabbit Monoclonal (RM396)
REV-31-1282-00
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCALD1
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-CALD1 (human), Rabbit Monoclonal (RM396)
- Delivery Days Customer5
- Antibody SpecificityThis antibody reacts to human CALD1 .
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM396
- FormulationLiquid
- Gene ID800
- Target nameCALD1
- Target descriptioncaldesmon 1
- Target synonymscaldesmon; CDM; HCAD; H-CAD; LCAD; L-CAD; NAG22; testis secretory sperm-binding protein Li 227n
- HostRabbit
- IsotypeIgG
- Protein IDQ05682
- Protein NameCaldesmon
- Scientific DescriptionCALD1 (Caldesmon) is a calmodulin binding protein. Like calponin, caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle. This calmodulin- and actin-binding protein plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca++-calmodulin, actin, tropomyosin, myosin and phospholipids. It is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca++-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. In diagnostic immunochemistry, caldesmon is a marker for smooth muscle differentiation. - Recombinant Antibody. This antibody reacts to human CALD1 . Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CALD1 (Caldesmon) is a calmodulin binding protein. Like calponin, caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle. This calmodulin- and actin-binding protein plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca++-calmodulin, actin, tropomyosin, myosin and phospholipids. It is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca++-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. In diagnostic immunochemistry, caldesmon is a marker for smooth muscle differentiation.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203