anti-Caspase 5 antibody

Arigo Biolaboratories

anti-Caspase 5 antibody

23

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

CASP5

caspase 5

caspase 5 variant X1; caspase 5, apoptosis-related cysteine peptidase; caspase 5, apoptosis-related cysteine protease; caspase-5; ICE(rel)III; ICEREL-III; ICH-3; protease ICH-3; protease TY; TY protease

Rabbit

IgG

Caspase-5 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1beta and IL-18. Caspase-5 can interact with caspase-1; both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1beta. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma.

-20°C

12352203