Anti-CD10 [SS2/36]

Absolute Antibody

Anti-CD10 [SS2/36]

7

This antibody recognises neprilysin which is a cell surface enzyme degrading various peptides, such as enkephalins, angiotensins and atrial natriuretic factor.

Anti-Neprilysin antibodies have been used in the characterisation and identification of certain cancers and other conditions. For instance, CD10 (Neprilysin) is an important cell surface marker of human acute lymphocytic leukemia (ALL) and Daskalopoulou and colleagues (2001) used this antibody (along with others) during cytological diagnosis and subclassification of malignant lymphomas as a marker of ALL. SS2/36 antibody was also used for flow cytometric phenotyping of hairy cell leukemia cases (Jasionowski et al., 2003).

Flow Cytometry, Western Blot, ImmunoHistoChemistry

IHC; FC; WB

Research Use Only

Monoclonal

SS2/36

MME

membrane metalloendopeptidase

atriopeptidase; CALLA; CD10; CMT2T; common acute lymphocytic leukemia antigen; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; NEP; neprilysin; neprilysin-390; neprilysin-411; neutral endopeptidase 24.11; SCA43; SFE; skin fibroblast elastase

Mouse

IgG1

Neprilysin

Human

Human

This antibody was raised by immunising mice with common acute lymphoblastic leukaemia cells.

-20°C,2°C to 8°C

12352203