Anti-CD117 [33G5]

Absolute Antibody

Anti-CD117 [33G5]

7

The antibody is specific for CD117. CD117 is a tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, ga

The antibody specifically detected CD117 protein in Western blot analysis. The antibody 33G5 and the commercial antibody YR145 were used to stain gastrointestinal stromal tumor tissue. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 33G5 was higher than the commercial antibody. The antibody and the commercially available antibody YR145 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN113621064A).

Western Blot, ELISA, ImmunoHistoChemistry

IHC; WB; ELISA

Research Use Only

Monoclonal

33G5

KIT

KIT proto-oncogene, receptor tyrosine kinase

CD117; C-Kit; c-Kit protooncogene; mast/stem cell growth factor receptor Kit; MASTC; p145 c-kit; PBT; piebald trait protein; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; SCFR; soluble KIT variant 1; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Rabbit

IgG

Mast/stem cell growth factor receptor Kit

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Human

Human

The original antibody was generated by immunizing mice with CD117.

-20°C,2°C to 8°C

12352203