Anti-CD134 [OX-40]

Absolute Antibody

Anti-CD134 [OX-40]

7

OX-40 antibody binds specifically to CD4+ T blasts. CD134 is a protein of the TNFR superfamily. It binds to OX40 ligand of both the monomeric and trimeric states which results in co-stimulated proliferation.

OX-40 antibody results in Fc-dependent (i.e. not Fab or F(ab)2) stimulation of in vitro activated T cell proliferation, but is not mitogenic for resting cells. This antibody can also label CD4+ T blasts and can pull down CD134/CD134+ cells.

Functional Assay, Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

FC; functional; FACS; IHC-fr; IP

Research Use Only

Monoclonal

OX-40

Tnfrsf4

TNF receptor superfamily member 4

MRC OX40; Ox40; OX40 antigen; OX40L receptor; Tax-transcriptionally activated glycoprotein 1; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor superfamily, member 4; Txgp1

Rat

IgG2b

Tumor necrosis factor receptor superfamily member 4

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Rat

Rat

OX40 antibody was prepared by immunizing mice with phytohaemagglutinin-activated rat lymph node cells.

-20°C,2°C to 8°C

12352203