anti-CD134 / OX40 antibody [OX-40] (FITC)
ARG23096
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityRat
TargetTnfrsf4
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD134 / OX40 antibody [OX-40] (FITC)
- Delivery Days Customer23
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDOX-40
- Concentration0.1 mg/ml
- ConjugateFITC
- Gene ID25572
- Target nameTnfrsf4
- Target descriptionTNF receptor superfamily member 4
- Target synonymsMRC OX40; Ox40; OX40 antigen; OX40L receptor; Tax-transcriptionally activated glycoprotein 1; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor superfamily, member 4; Txgp1
- HostMouse
- IsotypeIgG2b
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
- ReactivityRat
- Storage Instruction2°C to 8°C
- UNSPSC12352203