anti-CD155 (PVR) (human), mAb (ANC6A3) (R-PE)

Ancell Corporation

anti-CD155 (PVR) (human), mAb (ANC6A3) (R-PE)

10

Binds to cell surface CD155 on U-937 cells and to recombinant CD155 in ELISA assay. The antibody clones ANC6A3 and ANC2B2 (#ANC-255-020) bind to distict epitopes of CD155 and are suitable as a matched pair for a sandwich ELISA assay.

Flow Cytometry, ELISA

Research Use Only

Monoclonal

ANC6A3

0.5 mg/ml

RPE

>95%

Liquid

Mouse

IgG1

Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70 kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma. - Monoclonal antibody. Binds to cell surface CD155 on U-937 cells and to recombinant CD155 in ELISA assay. The antibody clones ANC6A3 and ANC2B2 (#ANC-255-020) bind to distict epitopes of CD155 and are suitable as a matched pair for a sandwich ELISA assay. Applications: ELISA, FACS. Isotype: Mouse IgG1kappa. Clone: ANC6A3. 50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70 kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma.

Human

2°C to 8°C

12352203