Anti-CD23 [5E3]

Absolute Antibody

Anti-CD23 [5E3]

7

This antibody is specific for human CD23. CD23 is a low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. It has essential roles in the regulation of IgE production and in the differentiation of B-cells.

To examine B1 and B2 cells for their ability to be rendered unresponsive by using an anti-lg tolerance protocol that is independent of receptor specificity, flow cytometry was performed on mouse splenic B cell suspensions using the mouse version of this antibody (Liou et al, 1995; pmid:7759864).

Flow Cytometry

FC

Research Use Only

Monoclonal

5E3

FCER2

Fc fragment of IgE receptor II

BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4, member J; Fc epsilon receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); FCE2; fc-epsilon-RII; IGEBF; immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; lymphocyte IgE receptor

Rabbit

IgG

Low affinity immunoglobulin epsilon Fc receptor

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Human, Mouse

Human, Mouse

The mouse version of this antibody was raised by immunizing a BALB/c mouse with Daudi (human Burkitt's lymphoma cell-line).

-20°C,2°C to 8°C

12352203