anti-CD23 (human), Rabbit Monoclonal (RM406)

RevMAb Biosciences

anti-CD23 (human), Rabbit Monoclonal (RM406)

5

This antibody reacts to human to CD23.

Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

RM406

Liquid

FCER2

Fc fragment of IgE receptor II

BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4, member J; Fc epsilon receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); FCE2; fc-epsilon-RII; IGEBF; immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; lymphocyte IgE receptor

Rabbit

IgG

Low affinity immunoglobulin epsilon Fc receptor

CD23 (Fc epsilon RII; FcepsilonRII) is a glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is a low-affinity receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, found on B cells. It is expressed on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. Functionally, CD23 is involved in B cell growth and differentiation and IgE production. CD23 is known to have a role of transportation in antibody feedback regulation. CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia. - Recombinant Antibody. This antibody reacts to human to CD23. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CD23 (Fc epsilon RII; FcepsilonRII) is a glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is a low-affinity receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, found on B cells. It is expressed on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. Functionally, CD23 is involved in B cell growth and differentiation and IgE production. CD23 is known to have a role of transportation in antibody feedback regulation. CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.

Human

-20°C,2°C to 8°C

12352203