Anti-CD3e [PC3/188A]

Absolute Antibody

Anti-CD3e [PC3/188A]

7

This antibody recognises CD3 epsilon which is a part of the TCR-CD3 complex present on all mature T-lymphocyte cells and is crucial in the adaptive immunity.

This anti-CD3 has been used for the identification of normal and malignant T lymphocytes in paraffin embedded or frozen tissue sections. For instance, one group labelled paraffin-embedded pancreatic sections with PC3/188A antibody to identify T-lymphocytes while investigating the role of the oligodeoxynucleotide IMT504 on diabetes in rats (Bianchi et al., 2012). Another group also used this antibody to identify T lymphocytes by staining rat brain tissue samples against CD3 in a study investigating the mechanisms of neuroinflammation (Doursout et al., 2013). Finally, Roballo and Bushman (2019) utilised PC3/188A antibody as a marker of T cells during immunohistochemical analysis of frozen sciatic nerve sections.

Western Blot, ImmunoHistoChemistry

IHC; WB

Research Use Only

Monoclonal

PC3/188A

CD3E

CD3e molecule

CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule, epsilon (CD3-TCR complex); CD3-epsilon; IMD18; T3E; T-cell antigen receptor complex, epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; TCRE

Human

IgG4

T-cell surface glycoprotein CD3 epsilon chain

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Bovine, Chicken, Equine, Guinea Pig, Human, Porcine, Primate, Rabbit, Rat

Cow, Chicken, Horse, Human, Guinea Pig, Pig, Primate, Rat, Rabbit

This antibody was raised by immunising mice with a peptide sequence (156-168) from the intracytoplasmic portion of the epsilon-chain of CD3.

-20°C,2°C to 8°C

12352203