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ProductsBack/Anti-CD44 [Hermes-1]

Anti-CD44 [Hermes-1]

Research Use Only
Ab00628-23.0
Absolute Antibody
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, Neutralisation/Blocking
Product group Antibodies
ReactivityBovine, Goat, Human, Mouse, Primate, Rabbit, Rat, Sheep
TargetCD44
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-CD44 [Hermes-1]
  • Delivery Days Customer
    7
  • Antibody Specificity
    This antibody is specific for CD44 (gp90 epitope cluster I), which is selectively expressed on normal or transformed lymphoid cells that are able to recognize and bind to high endothelial venules (specialized vessels that mediate lymphocyte exit from the
  • Application Supplier Note
    This antibody binds CD44, so can be used to label CD44+ cells in flow cytometry analysis. As CD44 molecules are used to bind to high endothelial venules (HEV) at the site of lymphoctye entry to lymphoid organs, this antibody can be used to specifically stain HEV-binding cell lines (Jalkanen, 1986). In addition, this antibody blocks the adhesion of the haematopoietic progenitor cell line KG1 to hyaluronic acid (Bendall, 2003), but does not block lymphocyte binding to HEV (Picker, 1989). 7H9D6 partially blocks the binding of this antibody.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, Neutralisation/Blocking
  • Applications Supplier
    Blocking; ELISA; FC; ICC/IF; IHC; IP; Neut; WB
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Hermes-1
  • Gene ID960
  • Target name
    CD44
  • Target description
    CD44 molecule (Indian blood group)
  • Target synonyms
    CD44 antigen; CDW44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; epican; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronate receptor; IN; Indian blood group antigen; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; phagocytic glycoprotein 1; soluble CD44
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP16070
  • Protein Name
    CD44 antigen
  • Scientific Description
    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity
    Bovine, Goat, Human, Mouse, Primate, Rabbit, Rat, Sheep
  • Reactivity Supplier
    Human, Mouse, Rat, Goat, Primate, Rabbit, Sheep, Bovine
  • Reactivity Supplier Note
    This antibody was produced by immunizing a Fischer rat with human tonsil lymphocytes (10^7cells intraperitoneally in Freund's complete adjuvant). A boost was given 2 weeks later (intravascularly in saline).
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203