Anti-CD44 [NKI-P1]

Absolute Antibody

Anti-CD44 [NKI-P1]

9

To determine the expression of CD44 in oral squamous cell carcinoma associated endothelial cells, immunohistochemistry was used on squamous cell carcinoma tissues using the mouse version of this antibody (Essa and Deraz, 2021). To explore the role of CD44 splicing in the regulation of cell binding to HA, flow cytometry was used on Namalwa and COS transfectants using the mouse version of this antibody (van der Voort, 2000). To study expression of CD44 in human colorectal cancer, immunohistochemistry was performed on normal and pathological tissue using the mouse version of this antibody (Wielenga et al, 1993; pmid:7691404). Immunohistochemistry was performed on normal and colorectal neoplasia tissue using the mouse version of this antibody to study expression of CD44 in normal tissue and colorectal neoplasia tissue (Heider et al, 1993; pmid:8416989). To study the expression of CD44 in primary brain tumours, flow cytometry was performed on glioma cell cultures using the mouse version of this antibody. Furthermore, primary brain tumours were stained for immunohistochemistry using this antibody (Kaaijk et al, 1995; pmid:8750184). An aggregation assay using the mouse version of this antibody was performed on JY, an EBV-transformed B cell line to demonstrate that triggering CD44 promotes cell adhesion (Koopman et al, 1990; pmid:2246503). To study the use of endothelial CD44 as a target for anticancer therapy, an immunotoxin assay was performed on HUVEC and the human CD44 expressing keratinocyte cell line HaCaT using the mouse version of this antibody (Griffioen et al, 1997; pmid:9242547).

Functional Assay, Flow Cytometry, ImmunoHistoChemistry

Research Use Only

Monoclonal

NKI-P1

CD44

CD44 molecule (IN blood group)

CDW44, CSPG8, ECM-III, ECMR-III, H-CAM, HCELL, HUTCH-1, HUTCH-I, Hermes-1, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CD44 antigen, CD44 molecule (Indian blood group), GP90 lymphocyte homing/adhesion receptor, Hermes antigen, In(Lu) related-p80, Indian blood group antigen, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, epican, extracellular matrix receptor III, hematopoietic cell E- and L-selectin ligand, heparan sulfate proteoglycan, homing cell adhesion molecule, homing function and Indian blood group system, hyaluronate receptor, phagocyte glycoprotein 1, phagocytic glycoprotein 1, soluble CD44

Rabbit

IgG

CD44 antigen

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Human

-20°C,2°C to 8°C

12352203