Anti-CD45R [RA3-6B2]

Absolute Antibody

Anti-CD45R [RA3-6B2]

9

This antibody is specific for murine CD45R antigen which is expressed on B lymphocytes throughout their development from early pro-B stages onwards and is down-regulated upon terminal differentiation to plasma cells. Apart from B cells, CD45R is expressed

This antibody has been used in FACS analyses, immunoprecipitation, immunoblotting, and immunohistochemistry in various studies, such as to understand the role of PD-1 in maintaining islet-specific tolerance in type 1 diabetes (Martinov et al, 2016), to investigate how Staphylococcus aureus enterotoxins spread systemically and trigger inflammatory cascades (Svedova et al, 2016), to highlight the physiologic importance of cell-type specific balancing of AhR/AhRR expression in response to microbial, nutritional and other environmental stimuli (Brandstaetter et al, 2016), and to examine the role of FBXW7 in suppression of cancer metastasis in a non-cell-autonomous manner (Yumimoto et al, 2015).

Flow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

Monoclonal

RA3-6B2

Ptprc

protein tyrosine phosphatase, receptor type, C

B220; Cd45; CD45R; L-CA; leukocyte common antigen; loc; Ly-; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-; Lyt-4; receptor-type tyrosine-protein phosphatase C; T200

Mouse

IgG2a

Receptor-type tyrosine-protein phosphatase C

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Mouse

-20°C,2°C to 8°C

12352203