Anti-CD79a [HM47]

Absolute Antibody

Anti-CD79a [HM47]

7

IP: HM47 antibody was successfully used in immunoprecipitation of samples coming from NP-40 lysates of surface-labelled Daudi cells what confirmed participation of the mb-1 gene product in mIgM-associated heterodimer; subsequently a reprecipitation was performed as a confirmatory step (van Noesel et al., 1991). IHC: This antibody presented strong selective staining of B cell follicles in sections of lymphoid tissue (Mason et al., 1991). HM47 showed also high specificity in staining bone marrow samples with acute promyelocytic leukemia (APL) (stained 86% APL cases and only 10% of non-APL samples) (Bhargava et al., 2007).

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

IHC; WB; IP

Research Use Only

Monoclonal

HM47

CD79A

CD79a molecule

IGA, IGAlpha, MB-1, MB1, B-cell antigen receptor complex-associated protein alpha chain, CD79a antigen (immunoglobulin-associated alpha), CD79a molecule, immunoglobulin-associated alpha, MB-1 membrane glycoprotein, ig-alpha, membrane-bound immunoglobulin-associated protein, surface IgM-associated protein

Mouse

IgG1

B-cell antigen receptor complex-associated protein alpha chain

Bovine, Chicken, Horse, Human, Guinea Pig, Mouse, Opossum, Pig, Primate, Rat, Rabbit

This antibody was raised by immunising BALB/c mice with a synthetic peptide G-T-Y-Q-D-V-G-S-L-N-I-A-D-V-Q, representing amino acids 202-216 of the human mb-1 protein and conjugated to thyroglobulin.

-20°C,2°C to 8°C

12352203