Anti-CD8 [51.1], Mouse IgG2b, Fc Silent(tm), kappa

Absolute Antibody

Anti-CD8 [51.1], Mouse IgG2b, Fc Silent(tm), kappa

9

The antibody could block HLA-A2.1-mediated binding to CD8alpha(+) expressed on CHO cells (Norment et al, 1988; PMID: 3263576). The antibody could also block TLA-mediated binding (Teitell et al., 1991; PMID: 1834760). The antibody was used to localize CD8alpha to the cell periphery on monocytes using confocal microscopy of permeabilized PBMC. The antibody could detect CD8alpha by flow cytometry on CD14hi monocytes from human peripheral blood (Gibbings et al. 2007; PMID: 17678538).

Flow Cytometry, Neutralisation/Blocking

Research Use Only

Monoclonal

51.1

CD8A

CD8 subunit alpha

CD8, CD8alpha, IMD116, Leu2, p32, T-cell surface glycoprotein CD8 alpha chain, CD8 antigen, alpha polypeptide (p32), CD8a molecule, Leu2 T-lymphocyte antigen, OKT8 T-cell antigen, T cell co-receptor, T-cell antigen Leu2, T-lymphocyte differentiation antigen T8/Leu-2, T8 T-cell antigen

Mouse

IgG2b

T-cell surface glycoprotein CD8 alpha chain

This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG2b format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203