Anti-CD8 [51.1], Mouse IgG2b, Fc Silent(tm), kappa

Absolute Antibody

Anti-CD8 [51.1], Mouse IgG2b, Fc Silent(tm), kappa

9

The antibody is specific for CD8.

The antibody could block HLA-A2.1-mediated binding to CD8alpha(+) expressed on CHO cells (Norment et al, 1988; PMID: 3263576). The antibody could also block TLA-mediated binding (Teitell et al., 1991; PMID: 1834760). The antibody was used to localize CD8alpha to the cell periphery on monocytes using confocal microscopy of permeabilized PBMC. The antibody could detect CD8alpha by flow cytometry on CD14hi monocytes from human peripheral blood (Gibbings et al. 2007; PMID: 17678538).

Flow Cytometry, Neutralisation/Blocking

Research Use Only

Monoclonal

51.1

CD8A

CD8a molecule

CD8; CD8 antigen, alpha polypeptide (p32); Leu2; Leu2 T-lymphocyte antigen; OKT8 T-cell antigen; p32; T cell co-receptor; T8 T-cell antigen; T-cell antigen Leu2; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2

Mouse

IgG2b

T-cell surface glycoprotein CD8 alpha chain

This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG2b format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203