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anti-CD8-alpha (mouse), mAb (53-6) (PE-Cy7)

Research Use Only
ANC-260-070
Ancell Corporation
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityMouse
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Ancell Corporation
  • Product Name
    anti-CD8-alpha (mouse), mAb (53-6) (PE-Cy7)
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    53-6
  • Conjugate
    Double Conjugated
  • Host
    Rat
  • Isotype
    IgG2a
  • Scientific Description
    CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-alpha chains binds to Class I MHC molecules alpha-3 domains. Defects in CD8A are a cause of familial CD8 deficiency [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. - Monoclonal Antibody. Isotype: Rat IgG2akappa. Clone: 53-6. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-alpha chains binds to Class I MHC molecules alpha-3 domains. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203