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ProductsBack/anti-CLDN 18.2 (Claudin-18.2), Rabbit Monoclonal (RM510)
Immunohistochemical staining of formalin-fixed and paraffin-embedded human stomach adenocarcinoma tissue sections using anti-CLDN18.2 Rabbit Monoclonal Antibody, Clone RM510, at 1:100 dilution.
Immunohistochemical staining of formalin-fixed and paraffin-embedded human stomach adenocarcinoma tissue sections using anti-CLDN18.2 Rabbit Monoclonal Antibody, Clone RM510, at 1:100 dilution.
Immunohistochemical staining of formalin-fixed and paraffin-embedded human stomach adenocarcinoma tissue sections using anti-CLDN18.2 Rabbit Monoclonal Antibody, Clone RM510, at 1:100 dilution.

anti-CLDN 18.2 (Claudin-18.2), Rabbit Monoclonal (RM510)

Research Use Only
REV-31-1402-00
RevMAb Biosciences
Product group Antibodies
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Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    anti-CLDN 18.2 (Claudin-18.2), Rabbit Monoclonal (RM510)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Scientific Description
    Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lungs. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung-specific. CLDN18.2 is maintained during the course of malignant transformation and is thus frequently displayed on the surface of human gastric cancer cells. - Recombinant Antibody. This antibody reacts to human CLDN18.2 (Claudin 18.2) (Isoform A2 of Claudin-18). This antibody may also react to mouse or rat CLDN18.2, as predicted by immunogen homology. Isotype: Rabbit IgG. Immunogen: A peptide corresponding to residues of human Claudin-18 Isoform A2. Applications: IHC. Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lungs. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung-specific. CLDN18.2 is maintained during the course of malignant transformation and is thus frequently displayed on the surface of human gastric cancer cells.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203