Immunohistochemical staining of formalin-fixed and paraffin-embedded human stomach adenocarcinoma tissue sections using anti-CLDN18.2 Rabbit Monoclonal Antibody, Clone RM510, at 1:100 dilution.
Immunohistochemical staining of formalin-fixed and paraffin-embedded human stomach adenocarcinoma tissue sections using anti-CLDN18.2 Rabbit Monoclonal Antibody, Clone RM510, at 1:100 dilution.
anti-CLDN 18.2, Rabbit Monoclonal (RM510)
REV-31-1402-00
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCLDN18
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-CLDN 18.2 (Claudin-18.2), Rabbit Monoclonal (RM510)
- Delivery Days Customer10
- Antibody SpecificityThis antibody reacts to human CLDN18.2 (Claudin 18.2) (Isoform A2 of Claudin-18). This antibody may also react to mouse or rat CLDN18.2, as predicted by immunogen homology.
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM510
- Gene ID51208
- Target nameCLDN18
- Target descriptionclaudin 18
- Target synonymsclaudin-18; SFTA5; SFTPJ; surfactant associated 5; surfactant associated protein J; surfactant, pulmonary associated protein J
- HostRabbit
- IsotypeIgG
- Protein IDP56856
- Protein NameClaudin-18
- Scientific DescriptionClaudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lungs. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung-specific. CLDN18.2 is maintained during the course of malignant transformation and is thus frequently displayed on the surface of human gastric cancer cells. - Recombinant Antibody. This antibody reacts to human CLDN18.2 (Claudin 18.2) (Isoform A2 of Claudin-18). This antibody may also react to mouse or rat CLDN18.2, as predicted by immunogen homology. Isotype: Rabbit IgG. Immunogen: A peptide corresponding to residues of human Claudin-18 Isoform A2. Applications: IHC. Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lungs. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung-specific. CLDN18.2 is maintained during the course of malignant transformation and is thus frequently displayed on the surface of human gastric cancer cells.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203