Anti-Cytokeratin 14 [2G4]

Absolute Antibody

Anti-Cytokeratin 14 [2G4]

9

This antibody is capable of binding human cytokeratin 14. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize in

The binding characterization of this antibody was done using ELISA. The original IgG1 antibody binds cytokeratin 5/6 with a high affinity constant of 4.8x 10^(8) M^(-1). This antibody was also used in the immunohistochemical analysis of frozen paraffin sections of tonsil tissues and esophageal squamous cell carcinoma. The immunohistochemical staining pattern of this antibody is similar to commercially available antibody L1002 (CN113087793).

ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

2G4

KRT14

keratin 14

CK14; cytokeratin 14; EBS3; EBS4; K14; keratin 14, type I; keratin, type I cytoskeletal 14; NFJ

Rabbit

IgG

Keratin, type I cytoskeletal 14

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Human

-20°C,2°C to 8°C

12352203