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Cytokeratin 14 antibody

GTX104124
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetKRT14
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cytokeratin 14 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.48 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3861
  • Target name
    KRT14
  • Target description
    keratin 14
  • Target synonyms
    CK14, EBS1, EBS1A, EBS1B, EBS1C, EBS1D, EBS3, EBS4, K14, NFJ, keratin, type I cytoskeletal 14, cytokeratin 14, keratin 14, type I
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP02533
  • Protein Name
    Keratin, type I cytoskeletal 14
  • Scientific Description
    This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Tang C, Liu C, Maffei B, et al. Primary ectocervical epithelial cells display lower permissivity to Chlamydia trachomatis than HeLa cells and a globally higher pro-inflammatory profile. Sci Rep. 2021,11(1):5848. doi: 10.1038/s41598-021-85123-7
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  • Kim JY, Ohn J, Yoon JS, et al. Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy. Nat Commun. 2019,10(1):3694. doi: 10.1038/s41467-019-11665-0
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  • Wang S, Qiu L, Meng X, et al. Knock-down of filaggrin influences the mitogen-activated protein kinases signaling pathway in normal human epidermal keratinocytes. Med Sci (Paris). 2018,34 Focus issue F1:94-98. doi: 10.1051/medsci/201834f116
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  • D'Amico S, Shi J, Martin BL, et al. STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis. Genes Dev. 2018,32(17-18):1175-1187. doi: 10.1101/gad.311852.118
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  • Fan JR, Lee HT, Lee W, et al. Potential role of CBX7 in regulating pluripotency of adult human pluripotent-like olfactory stem cells in stroke model. Cell Death Dis. 2018,9(5):502. doi: 10.1038/s41419-018-0519-8
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  • Lee YL, Lin KL, Chuang SM, et al. Elucidating Mechanisms of Bladder Repair after Hyaluronan Instillation in Ketamine-Induced Ulcerative Cystitis in Animal Model. Am J Pathol. 2017,187(9):1945-1959. doi: 10.1016/j.ajpath.2017.06.004
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  • Dang NN, Pang SG, Song HY, et al. Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response. Braz J Med Biol Res. 2015,48(1):39-45.
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  • Dang N, Pang S, Song H, et al. Knockdown of filaggrin influences the epidermal terminal differentiation via MAPK pathway in normal human epidermal keratinocytes. Mol Biol Rep. 2015,42(2):337-43. doi: 10.1007/s11033-014-3765-6
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