Anti-DR5 [YSd1]

Absolute Antibody

Anti-DR5 [YSd1]

7

YSd1 bound DR5 with high affinity, shown using competitive phage ELISA as well as surface plasmon resonance (with a Kd of 34 nM). By binding to interfacial regions of DR5 which are sites of physiological ligand interaction, it is likely that YSd1 has the capacity to neutralise DR5 activity by inhibition of downstream signalling.

Neutralisation/Blocking

NTRL

Research Use Only

Tumor necrosis factor receptor superfamily member 10B

This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203