DR5 peptide

GeneTex

DR5 peptide

9

The peptide is used for blocking the activity of DR5 (CT) (GTX28416). Incubatingthe peptide with equal volume of antibody for 30 min at 37C usually completely blocks theantibody activity.

Neutralisation/Blocking

Research Use Only

0.20 mg/ml

Unconjugated

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including tumor necrosis factor (TNF) and Fas ligand in the TNF family through their death domain containing receptors, TNF receptor 1 (TNFR1) and Fas, respectively. Another member in the TNF family has been identified and designated TRAIL (for TNF related apoptosis inducing ligand) and Apo2L (for Apo2 ligand). Receptors for TRAIL include two death domain containing receptors, DR4 and DR5, as well as two decoy receptors, DcR1 and DcR2, lacking the intracellular signaling death domain.

-20°C

12352202