Anti-E1 protein [DC1.56]

Absolute Antibody

Anti-E1 protein [DC1.56]

9

This antibody binds the E1 protein of the Chikungunya virus (CHIKV), which is the causative agent of zoonotic disease in humans called Chikungunya. Additionally, this antibody also cross reacts with multiple arthritogenic alphaviruses like Mayaro virus (M

The binding characterization of the IgG antibody for CHIKV E1 protein was done using ELISA and Biolayer interferometry (BLI). This antibody was capable of binding biotinylated p62-E1 hybrid protein in a flow cytometric assay. This antibody was also capable of immunoprecipitating the E1 envelope protein of CHIKV. The binding affinity of the original IgG antibody towards E1 protein was found to be Kd = 1.75 nM (PMID: 31697791).

Flow Cytometry, ImmunoPrecipitation, ELISA

Research Use Only

Monoclonal

DC1.56

CHIKVgp2

structural polyprotein

CHIKVgp2; structural polyprotein

Mouse

IgG1

Structural polyprotein

Virus

-20°C,2°C to 8°C

12352203