Anti-EGFR domain III [h-R3 (Nimotuzumab)]

Absolute Antibody

Anti-EGFR domain III [h-R3 (Nimotuzumab)]

9

This antibody binds to human EGFR and inhibits EGF-dependent clonogenic growth of NRK cells and completely blocks EGF stimulated autophosphorylation of the receptor (Fernandez 1992)

Flow Cytometry, ImmunoHistoChemistry, Neutralisation/Blocking

Research Use Only

Monoclonal

h-R3 (Nimotuzumab)

EGFR

epidermal growth factor receptor

ERBB, ERBB1, ERRP, HER1, NISBD2, NNCIS, PIG61, mENA, epidermal growth factor receptor, EGFR vIII, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, epidermal growth factor receptor tyrosine kinase domain, erb-b2 receptor tyrosine kinase 1, proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1

Mouse

IgG2a

Epidermal growth factor receptor

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

41116161