Anti-EGFRvIII [L8A4]
AB00184-23.0-BT
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry, Other Application
Product group Antibodies
ReactivityHuman
TargetEGFR
Overview
- SupplierAbsolute Antibody
- Product NameAnti-EGFRvIII [L8A4]
- Delivery Days Customer9
- Antibody SpecificityBinds EGFRvIII, a mutated form of EGFR, plays a prominent role in tumorigenesis.
- Application Supplier NoteThis antibody can be used to detect EGFRvIII, a mutated EGFR variant, in immunohistochemical staining, Western Blot, ELISA and flow-cytometry. Chou et al (2016, PMID: 27825958) used this antibody to detect EGFRvIII in acetone and PFA fixed sections by fluorescent immunohistochemistry.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDL8A4
- Gene ID1956
- Target nameEGFR
- Target descriptionepidermal growth factor receptor
- Target synonymsavian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
- HostRabbit
- IsotypeIgG
- Protein IDP00533
- Protein NameEpidermal growth factor receptor
- Scientific DescriptionThis chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203