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Anti-EGFRvIII [L8A4]

Research Use Only
AB00184-23.0-BT
Absolute Antibody
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry, Other Application
Product group Antibodies
ReactivityHuman
TargetEGFR
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-EGFRvIII [L8A4]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Binds EGFRvIII, a mutated form of EGFR, plays a prominent role in tumorigenesis.
  • Application Supplier Note
    This antibody can be used to detect EGFRvIII, a mutated EGFR variant, in immunohistochemical staining, Western Blot, ELISA and flow-cytometry. Chou et al (2016, PMID: 27825958) used this antibody to detect EGFRvIII in acetone and PFA fixed sections by fluorescent immunohistochemistry.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    L8A4
  • Gene ID1956
  • Target name
    EGFR
  • Target description
    epidermal growth factor receptor
  • Target synonyms
    avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP00533
  • Protein Name
    Epidermal growth factor receptor
  • Scientific Description
    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203