Anti-EGFRvIII [L8A4]

Absolute Antibody

Anti-EGFRvIII [L8A4]

9

Binds EGFRvIII, a mutated form of EGFR, plays a prominent role in tumorigenesis.

This antibody can be used to detect EGFRvIII, a mutated EGFR variant, in immunohistochemical staining, Western Blot, ELISA and flow-cytometry. Chou et al (2016, PMID: 27825958) used this antibody to detect EGFRvIII in acetone and PFA fixed sections by fluorescent immunohistochemistry.

Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry, Other Application

Research Use Only

Monoclonal

L8A4

EGFR

epidermal growth factor receptor

avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1

Mouse

IgG2a

Epidermal growth factor receptor

This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against human EGFRvIII (Fab) and one arm directed against mouse CD3e (scFv).

Human

-20°C,2°C to 8°C

12352203