Anti-EGFRvIII [L8A4]

Absolute Antibody

Anti-EGFRvIII [L8A4]

9

Binds EGFRvIII, a mutated form of EGFR, plays a prominent role in tumorigenesis.

This antibody can be used to detect EGFRvIII, a mutated EGFR variant, in immunohistochemical staining, Western Blot, ELISA and flow-cytometry. Chou et al (2016, PMID: 27825958) used this antibody to detect EGFRvIII in acetone and PFA fixed sections by fluorescent immunohistochemistry.

L8A4

EGFR

epidermal growth factor receptor

avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1

Epidermal growth factor receptor

This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against human EGFRvIII (Fab) and one arm directed against mouse CD3e (scFv).

-20°C,2°C to 8°C

12352203