Anti-EP-CAM [4B5E6D7]

Absolute Antibody

Anti-EP-CAM [4B5E6D7]

7

The antibody is specific for EP-CAM. EP-CAM is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. It may act as a phys

The antibody 4B5E6D7 and the commercial antibody MOC-31 were used to stain lung squamous cell carcinoma, lung adenocarcinoma, cervical cancer, colorectal carcinoma, duodenum and rectal tissues. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 4B5E6D7 was higher than the commercial antibody. The antibody and the commercially available antibody MOC-31 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN110922485B).

Western Blot, ELISA, ImmunoHistoChemistry

IHC; WB; ELISA

Research Use Only

Monoclonal

4B5E6D7

EPCAM

epithelial cell adhesion molecule

adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; DIAR5; EGP-2; EGP314; EGP40; epithelial cell adhesion molecule; epithelial glycoprotein 314; ESA; HNPCC8; human epithelial glycoprotein-2; KS1/4; KSA; M4S1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; TACSTD1; TROP1; trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1

Rabbit

IgG

Epithelial cell adhesion molecule

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Human

Human

The original antibody was generated by immunizing BALB/c mice with EP-CAM.

-20°C,2°C to 8°C

12352203