Anti-ESR1 Antibody

HUABIO

Anti-ESR1 Antibody

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

ESR1

estrogen receptor 1

ER, ESR, ESRA, ESTRR, Era, NR3A1, estrogen receptor, E2 receptor alpha, ER-alpha, estradiol receptor, estrogen nuclear receptor alpha, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, nuclear receptor subfamily 3 group A member 1, oestrogen receptor alpha

Rabbit

IgG

Estrogen receptor

Estrogen receptor alpha (ERalpha), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen. In humans, ERalpha is encoded by the gene ESR1 (EStrogen Receptor 1). The estrogen receptor (ESR) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The ESR1 protein localizes to the nucleus where it may forms a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

Human

-20°C,2°C to 8°C

41116161