Figure 1: Detection of endogenous mouse GLUT2 in mouse liver and brain (low expression control) membranes by immunoblotting using anti-GLUT2 (mouse), pAb (IN118) (Prod. No. AG-25B-0042).
Figure 1: Detection of endogenous mouse GLUT2 in mouse liver and brain (low expression control) membranes by immunoblotting using anti-GLUT2 (mouse), pAb (IN118) (Prod. No. AG-25B-0042).
anti-GLUT2 (mouse), pAb (IN118)
AG-25B-0042
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityMouse
TargetSlc2a2
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-GLUT2 (mouse), pAb (IN118)
- Delivery Days Customer10
- Antibody SpecificityRecognizes mouse GLUT2.
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- Estimated Purity>95%
- FormulationLiquid
- Gene ID20526
- Target nameSlc2a2
- Target descriptionsolute carrier family 2 (facilitated glucose transporter), member 2
- Target synonymsAI266973; glucose transporter type 2, liver; Glut; Glut-; Glut2; Glut-2; liver-type glucose transporter; solute carrier family 2, facilitated glucose transporter member 2
- HostRabbit
- Protein IDP14246
- Protein NameSolute carrier family 2, facilitated glucose transporter member 2
- Scientific DescriptionGLUT2 belongs to the family of glucose transporters (GLUTs, encoded by the SLC2A genes), which comprises 14 isoforms. GLUT2 has a uniquely low affinity for glucose (Km ~ 17mmol/l), and can also use mannose, galactose and fructose as low-affinity substrates. However, it has a high affinity for glucosamine (Km ~ 0.8mmol/l). GLUT2 is expressed in liver, intestine, kidney and pancreatic islet beta cells, as well as in the central nervous system, in neurons, astrocytes and tanycytes. Physiological studies of genetically modified mice have revealed a role for GLUT2 in several regulatory mechanisms. GLUT2 is also the major glucose transporter in the plasma membrane of hepatocytes. In pancreatic beta cells, GLUT2 is required for glucose-stimulated insulin secretion. In the nervous system, GLUT2-dependent glucose-sensing controls feeding, thermoregulation and pancreatic islet cell mass and function, as well as sympathetic and parasympathetic activities. - Polyclonal Antibody. Recognizes mouse GLUT2. Applications: IHC, IP, WB. Source: Rabbit. GLUT2 belongs to the family of glucose transporters (GLUTs, encoded by the SLC2A genes), which comprises 14 isoforms. GLUT2 has a uniquely low affinity for glucose (Km ~ 17mmol/l), and can also use mannose, galactose and fructose as low-affinity substrates. However, it has a high affinity for glucosamine (Km ~ 0.8mmol/l). GLUT2 is expressed in liver, intestine, kidney and pancreatic islet beta cells, as well as in the central nervous system, in neurons, astrocytes and tanycytes. Physiological studies of genetically modified mice have revealed a role for GLUT2 in several regulatory mechanisms. GLUT2 is also the major glucose transporter in the plasma membrane of hepatocytes. In pancreatic beta cells, GLUT2 is required for glucose-stimulated insulin secretion. In the nervous system, GLUT2-dependent glucose-sensing controls feeding, thermoregulation and pancreatic islet cell mass and function, as well as sympathetic and parasympathetic activities.
- ReactivityMouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203