Anti-Glypican 3 [4C11]

Absolute Antibody

Anti-Glypican 3 [4C11]

9

This antibody binds human glypican 3 (GPC3).Glypican-3 is an oncofetal antigen that belongs to the glypican family of glycosyl-phosphatidylinositol-anchored heparin sulfate proteoglycans. It negatively regulates the hedgehog signaling pathway and positive

The initial binding characterization of this antibody was done using ELISA. This antibody can identify human glypican 3 expressed on the Huh7, LM3, HepG2, PLC, PVTT and SMMC-7721 (7721) cell lysates in a western blot assay. This antibody was also used in the immunohistochemical staining of human liver cancer tissues (CN111040036).

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

4C11

GPC3

glypican 3

DGSX; glypican proteoglycan 3; glypican-3; GTR2-2; heparan sulphate proteoglycan; intestinal protein OCI-5; MXR7; OCI-5; SDYS; secreted glypican-3; SGB; SGBS; SGBS1

Human

IgG1

Glypican-3

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Human

-20°C,2°C to 8°C

12352203