Bio-Connect

Anti-Hu CD146 APC

1A-783
EXBIO
ApplicationsFlow Cytometry
Product group Antibodies
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Overview

  • Supplier
    EXBIO
  • Product Name
    Anti-Hu CD146 APC
  • Delivery Days Customer
    7
  • Application Supplier Note
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clone ID
    P1H12
  • Conjugate
    APC (Allophycocyanin)
  • Isotype
    IgG1
  • Scientific Description
    CD146, also known as MCAM (melanoma cell adhesion molecule) or MUC18, is a heavily glycosylated transmembrane glycoprotein with more than 50% of the mass from carbohydrates. It is expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, activated T cells and activated keratinocytes, and on some cancer cells, especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203