Anti-Hu CD163 Biotin
1B-645
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
Overview
- SupplierEXBIO
- Product NameAnti-Hu CD163 Biotin
- Delivery Days Customer7
- Application Supplier NoteFlow cytometry: Recommended dilution: 1-5 microg/ml.
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- Clone IDGHI/61
- Concentration1 mg/ml
- ConjugateBiotin
- IsotypeIgG1
- Scientific DescriptionCD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203






