Anti-Hu CD263 APC

EXBIO

Anti-Hu CD263 APC

7

Flow cytometry: Recommended dilution: 1-5 microg/ml.

Flow Cytometry

Research Use Only

TRAIL-R3-02

0.1 mg/ml

APC (Allophycocyanin)

IgG1

TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).

Human

2°C to 8°C

12352203