Bio-Connect

Anti-Hu CD266 APC

1A-755
EXBIO
ApplicationsFlow Cytometry
Product group Antibodies
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Overview

  • Supplier
    EXBIO
  • Product Name
    Anti-Hu CD266 APC
  • Delivery Days Customer
    7
  • Application Supplier Note
    Flow cytometry: Recommended dilution: 5-15 microg/ml. Extracellular and intracellular staining.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clone ID
    ITEM-4
  • Concentration
    0.1 mg/ml
  • Conjugate
    APC (Allophycocyanin)
  • Isotype
    IgG2b
  • Scientific Description
    CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203