Anti-Hu CD334 Purified

EXBIO

Anti-Hu CD334 Purified

7

Flow cytometry: Recommended dilution: 2-6 microg/ml.

Flow Cytometry, ImmunoCytoChemistry

Research Use Only

4FR6D3

1 mg/ml

IgG1

CD334 / FGFR4 (fibroblast growth factor receptor 4), a transmembrane tyrosine kinase, which is expressed in many tissues, such as in lung, kidney, muscle, heart, pancreas, intestine and other, acts as a receptor for several fibroblast growth factors, namely FGF1, FGF2, FGF6, FGF8, and FGF19. Interaction with these growth factors initiates in cell the signaling cascades leading to the mitogenesis and cell differentiation. Presence of CD334 Gly338Arg allele correlates with prognostic parameters in various cancer studies. CD334 plays multiple roles in the organism, including those of muscle regeneration, cholesterol-to-bile acid metabolism, or glucose homeostasis.

Human

2°C to 8°C

12352203