Biotin Anti-Human CD45RA Antibody[HI100]

Elabscience

Biotin Anti-Human CD45RA Antibody[HI100]

12

Flow Cytometry

Research Use Only

Monoclonal

HI100

0.5 mg/ml

Biotin

PTPRC

protein tyrosine phosphatase receptor type C

B220, CD45, CD45R, GP180, IMD105, L-CA, LCA, LY5, T200, receptor-type tyrosine-protein phosphatase C, CD45 antigen, T200 glycoprotein, T200 leukocyte common antigen, glycoprotein 180, protein tyrosine phosphatase, receptor type, c polypeptide

Mouse

IgG2b

Receptor-type tyrosine-protein phosphatase C

CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

2°C to 8°C

41116161