Immunohistochemical staining of formalin fixed and paraffin embedded human glioblastoma using Anti-IDH1(R132H) Rabbit Monoclonal Antibody (Clone RM390) at a 1:100 dilution.
anti-IDH1 (R132H) (human), Rabbit Monoclonal (RM390)
REV-31-1276-00
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-IDH1 (R132H) (human), Rabbit Monoclonal (RM390)
- Delivery Days Customer5
- Antibody SpecificityThis antibody reacts to human IDH1(R132H).
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM390
- FormulationLiquid
- Gene ID3417
- Target nameIDH1
- Target descriptionisocitrate dehydrogenase (NADP(+)) 1
- Target synonymsepididymis luminal protein 216; epididymis secretory protein Li 26; epididymis secretory sperm binding protein; HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; isocitrate dehydrogenase (NADP(+)) 1, cytosolic; isocitrate dehydrogenase [NADP] cytoplasmic; isocitrate dehydrogenase 1 (NADP+), soluble; NADP(+)-specific ICDH; NADP-dependent isocitrate dehydrogenase, cytosolic; NADP-dependent isocitrate dehydrogenase, peroxisomal; oxalosuccinate decarboxylase; PICD
- HostRabbit
- IsotypeIgG
- Protein IDO75874
- Protein NameIsocitrate dehydrogenase [NADP] cytoplasmic
- Scientific DescriptionIsocitrate Dehydrogenase 1 (IDH1) is a soluble, cytosolic enzyme involved in the TCA metabolic cycle. The most notable mutation in this enzyme, R132H, is clinically indicated in the majority of astrocytomas and oligodendroglial tumors, with the mutation being associated with more favourable prognosis and increased survival in those patients. IDH1 R132H is also useful in the differential diagnosis between anaplastic glioma and glioblastoma. - Recombinant Antibody. This antibody reacts to human IDH1(R132H). Applications: IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Isocitrate Dehydrogenase 1 (IDH1) is a soluble, cytosolic enzyme involved in the TCA metabolic cycle. The most notable mutation in this enzyme, R132H, is clinically indicated in the majority of astrocytomas and oligodendroglial tumors, with the mutation being associated with more favourable prognosis and increased survival in those patients. IDH1 R132H is also useful in the differential diagnosis between anaplastic glioma and glioblastoma.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203