Anti-IGF1R [IGFR 24-31]

Absolute Antibody

Anti-IGF1R [IGFR 24-31]

7

The ability of this antibody to bind human IGF1R has been confirmed in IGF1 binding assays using both IG1FR-overexpressing IGF1R/3T3 cells and soluble receptors (Soos et al, 1992).This antibody efficiently precipitates IGF1R solubilized from IGF1R/3T3 cells and receptor-IGF1 complexes (Soos et al, 1992). When immobilised, this antibody has been shown to remove essentially all soluble IGF1R in immunodepletion experiments (Soos et al, 1992). Additionally, this antibody has been used, as part of a panel, in the immunohistochemical staining of large cell neuroendocrine carcinoma and small cell lung carcinoma (Nitadori et al, 2006) and breast carcinoma tissue microarray samples (Hartog et al, 2011).

ImmunoPrecipitation, ImmunoHistoChemistry

IP; IHC

Research Use Only

Insulin-like growth factor 1 receptor

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203