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anti-IKB beta phospho (Ser23) antibody

ARG51779
Arigo Biolaboratories
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNFKBIB
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-IKB beta phospho (Ser23) antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4793
  • Target name
    NFKBIB
  • Target description
    NFKB inhibitor beta
  • Target synonyms
    ikappaBbeta; I-kappa-B-beta; IKBB; ikB-B; ikB-beta; NF-kappa-B inhibitor beta; NF-kappa-BIB; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP9; TRIP-9
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203

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