Anti-Il-8 [5.12.14]

Absolute Antibody

Anti-Il-8 [5.12.14]

7

This antibody recognises Interleukin-8 (Il-8) which is a neutrophil chemotactic peptide. It is secreted by many different cells which had been activated by inflammatory stimuli. It is specific to Il-8 and does not bind to other chemokins, such as C5a, pla

This antibody is an Il-8 antagonist and prevents binding to neutrophils, which might be used in research aiming at treating asthma (before or after its onset) (US5874080A). Furthermore, this antibody inhibits both Il-8-dependent neutrophil chemotaxis and neutrophil elastase release (US5874080A).

Western Blot, ELISA, Neutralisation/Blocking

inhibition; blocking; WB; ELISA

Research Use Only

Monoclonal

5.12.14

CXCL8

C-X-C motif chemokine ligand 8

alveolar macrophage chemotactic factor I; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; emoctakin; GCP1; GCP-1; granulocyte chemotactic protein 1; IL8; interleukin 8; interleukin-8; LECT; LUCT; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; LYNAP; MDNCF; MONAP; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; NAF; NAP1; NAP-1; neutrophil-activating peptide 1; SCYB8; small inducible cytokine subfamily B, member 8; T-cell chemotactic factor; tumor necrosis factor-induced gene 1

Human

IgG4

Interleukin-8

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

This antibody was raised by immunising Balc/c mice against conjugated Il-8.

-20°C,2°C to 8°C

12352203