Anti-IL-9R [AH9R2]

Absolute Antibody

Anti-IL-9R [AH9R2]

9

This antibody binds specifically to the human IL-9 receptor alpha chain.

This antibody has been used to immunoprecipitate human IL-9R expressed by murine BW5147 cells transfected with hIL-9R-encoding cDNA (Demoulin et al, 1996). This antibody binds to and blocks the human IL-9Ra, and displays intermediate inhibitory activity; in a TS1H9RA3 proliferation assay, half-maximal inhibition of 100 pg/ml human IL-9 requires 10 mg/ml of this antibody (de Smedt et al, 2000). Equally, treatment with this antibody partially reduces the cellularity of human thymocytes in chimeric human-mouse FTOC, with no effect on murine thymocytes (de Smedt et al, 2000).

ImmunoPrecipitation, Neutralisation/Blocking

Research Use Only

Monoclonal

AH9R2

IL9R

interleukin 9 receptor

CD129; IL-9 receptor; IL-9R; interleukin-9 receptor

Mouse

IgG2b

Interleukin-9 receptor

Human

-20°C,2°C to 8°C

12352203