Anti-LAG3 [AbAbLAG3]

Absolute Antibody

Anti-LAG3 [AbAbLAG3]

9

The antibody is specific for LAG3. Lymphocyte activation gene 3 protein is an inhibitory receptor on antigen activated T-cells. It delivers inhibitory signals upon binding to ligands, such as FGL1.

The binding characterization of this antibody to human LAG3-Fc fusion protein was done using ELISA. The original human IgG antibody was reported to bind human LAG-3 in the sub picomolar range. This antibody was effective in inhibiting the binding of LAG3 to MHC class II molecules in an in vitro binding assay. In the antigen-specific T cell response assay, this antibody can stimulate the production of IL-2 (CN109748963).

ELISA, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

AbAbLAG3

LAG3

lymphocyte activating 3

CD223; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3

Human

IgG1

Lymphocyte activation gene 3 protein

This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203