Anti-M-CSF [MC3], Human IgG1, Fc Silent(tm), kappa

Absolute Antibody

Anti-M-CSF [MC3], Human IgG1, Fc Silent(tm), kappa

9

The antibody is specific for M-CSF. The antibody binds to a linear epitope represented by ITFEFVDQE amino acids 65-73 of M-CSF.

The binding properties of the original format of the antibody were analyzed using SPR analyses (Kd = 0.27 nM). The antibody could neutralize human M-CSF activity, as measured by a proliferation assay with M-NFS-60 cell line (EP1913028B1).

Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

MC3

CSF1

colony stimulating factor 1

colony stimulating factor 1 (macrophage); CSF-1; lanimostim; macrophage colony stimulating factor 1; macrophage colony-stimulating factor 1; MCSF

Human

IgG1

Macrophage colony-stimulating factor 1

This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203