anti-MEF2A phospho (Ser408) antibody

Arigo Biolaboratories

anti-MEF2A phospho (Ser408) antibody

23

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

MEF2A

myocyte enhancer factor 2A

ADCAD1; MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A); mef2; myocyte-specific enhancer factor 2A; RSRFC4; RSRFC9; serum response factor-like protein 1

Rabbit

IgG

The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes agamous and deficiens and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain

Human

-20°C

12352203