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ProductsBack/Anti-Mouse CD40 Monoclonal Antibody(PE Conjugated)

Anti-Mouse CD40 Monoclonal Antibody(PE Conjugated)

Anti-Mouse CD40 Monoclonal Antibody(PE Conjugated)

E-AB-F1028D

Product group Antibodies

Overview

Supplier
Elabscience
Product Name
Anti-Mouse CD40 Monoclonal Antibody(PE Conjugated)
Delivery Days Customer
12
Certification
Research Use Only
Scientific Description
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
UNSPSC
12352203

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