Anti-MSH2 [1B11-14-16]

Absolute Antibody

Anti-MSH2 [1B11-14-16]

9

This antibody binds an epitope on the human DNA mismatch protein MSH2 between amino acids 919-934 (NSFVNEIISRIKVTT). MSH2 forms a heterodimer with MSH6 to make the human MutSalpha mismatch repair complex. The DNA mismatch repair system (MMR) is composed o

The binding specificity of this antibody for human MSH2 was determined using ELISA. This antibody was capable of detecting MSH2 from HCT8 and Biu-87 cell lysates in a western blot. This antibody was also used in the immunohistochemical analysis of normal tissues like tonsil, appendix tissues and cancerous tissues like colorectal and bladder cancer. This antibody shows similar staining of MSH2 protein compared to the commercially available antibody G219-1129 (CN110218251).

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

1B11-14-16

MSH2

mutS homolog 2

COCA1; DNA mismatch repair protein Msh2; DNA mismatch repair protein Msh2 transcript; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2; mutS homolog 2, colon cancer, nonpolyposis type 1

Rabbit

IgG

DNA mismatch repair protein Msh2

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Human

-20°C,2°C to 8°C

12352203